Introduction to Multilevel Analysis

In this era of large-scale, multi-institutional studies, the importance analyzing hierarchical (clustered) data is increasing. However, conventional regression analysis may be inadequate for purpose because it assumes that records individual patients are independent other patients. Multilevel a statistical method allows one to analyze with structure. Mixed-effect models expand by incorporating random coefficients each unit cluster. can applied studies on repeated measures among individuals, effects individual-level variables, and cluster-level variables or variances. This report summarizes basics multilevel how used in clinical epidemiology research.